Edited by David Male, MA, PhD, Professor of Biology, Department of Life Sciences, The Open University, Milton Keynes, UK; Jonathan Brostoff, MA, DM, DSc(Med), FRCP, FRCPath, Professor Emeritus of Allergy and Environmental Health, King's College London, London, UK; David Roth, MD, PhD, Simon Flexner Professor and Chair of Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA and Ivan Roitt, DSc HonFRCP FRCPath FRS, Hon Director, Middlesex Centre for Investigative & Diagnostic Oncology, School of Health & Social Sciences, Middlesex University, London, UK